Research
The lab’s software rests on a real research record: an MD, a PhD in Integrative Genetics and Genomics, peer-reviewed publications in epigenetics and neurogenetic disease, a funded industry research grant, plus NIH fellowship and training-grant credentials.
Who does the research
Oren Fugón, MD-PhD holds an MD and a PhD in Integrative Genetics and Genomics from UC Davis (2023). His doctoral work centered on epigenetic editing in neurogenetic disease, specifically dCas9-based reactivation of the silenced paternal UBE3A allele in Angelman syndrome, co-mentored by Dr. David J. Segal and Dr. Janine LaSalle. He is Chief Science Officer at iVista Medical Education and is bilingual in English and Spanish. He publishes as Gutierrez Fugón OJ.
Peer-reviewed publications
Both papers below are open access.
First author, 2024
Gutierrez Fugón OJ, Sharifi O, Heath N, Soto DC, Gomez JA, Yasui DH, Mendiola AJP, O’Geen H, Beitnere U, Tomkova M, Haghani V, Dillon G, Segal DJ, LaSalle JM. Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons. Human Molecular Genetics. 2024, 33(19), 1711–1725.
Co-author, 2022
Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Gutierrez Fugón OJ, Walker CK, Ozonoff S, Daniels J, Grosvenor LP, Volk HE, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM. Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Genome Biology. 2022, 23, 46.
Grants and fellowships
Biogen-supported research grant (authored, funded)
Wrote the full Biogen-supported research grant at UC Davis, co-mentored by Dr. David J. Segal and Dr. Janine LaSalle. The grant was awarded and the project was funded. Authorship covered specific aims, research strategy and rationale, milestones, budget, plus the progress-reporting framework.
NIH F31 predoctoral fellowship (authored)
Authored and submitted an NIH F31 / NRSA predoctoral fellowship application at UC Davis. The package covered research strategy, specific aims, biosketch materials, plus the full assembled e-submission. It was submitted. It wasn’t awarded.
NIH T32 training-grant appointments
- NIH MCB T32 in Molecular and Cellular Biology, UC Davis. Accepted 2018, extended 2019.
- NIH EHS T32 in Environmental Health Sciences, UC Davis. Awarded 2018, declined after accepting the MCB T32.
These are competitive trainee appointments on institutional T32 mechanisms, not investigator-initiated research grants.
Pipeline and undergraduate training awards
- NIH IMSD Trainee, 2017
- NIH MARC Scholar, 2015
- NIH MHIRT, King’s College London, 2015
- NIH Bridges to Baccalaureate, UC Irvine, 2014
- NSF URM, 2014
Where the research shows up in the software
Biostatistics you can defend
CMEye goes past charting pre/post scores. It picks the right test for the data it’s given and reports effect sizes next to p-values, because a grant reviewer will ask. Years of running study statistics is why that behavior is the default.
Reference discipline
Every citation in a CME proposal is NLM-formatted and full-text verified, then audited for industry-sponsor bias. If a citation can’t be verified on its own, it gets cut. That habit came from writing a funded grant, not from a style guide.
Simulation over point estimates
Genomics teaches you not to trust a single number without a distribution around it. That’s why TankOdds reports the full spread of draft outcomes rather than one projection, and why the outcomes work reports effect sizes and uncertainty instead of a bare figure. See How It Works.
Collaborate
Open to research collaborations, biostatistics consulting, scientific writing, plus grant-writing engagements, academic or industry.
Contact: ixotronic@tetragammatronlabs.com · Download CV (PDF)